2018-04-15.

• Database (version 92.01)
  • Update to Genomicus92.01 with the last Ensembl data (release 92)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).

2017-12-22.

• Database (version 91.01)
  • Update to Genomicus91.01 with the last Ensembl data (release 91)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).

2017-10-15.

• Database (version 90.01)
  • Update to Genomicus90.01 with the last Ensembl data (release 90)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Two new functionalities: MultiKaryoView and PhylDiag Computation tools

2017-06-15.

• Database (version 89.01)
  • Update to Genomicus89.01 with the last Ensembl data (release 89)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2017-04-15.

• Database (version 88.01)
  • Update to Genomicus87.01 with the last Ensembl data (release 88)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2016-12-28.

• Database (version 87.01)
  • Update to Genomicus87.01 with the last Ensembl data (release 87)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2016-10-15.

• Database (version 86.01)
  • Update to Genomicus86.01 with the last Ensembl data (release 86)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2016-08-18.

• Database (version 85.01)
  • Update to Genomicus85.01 with the last Ensembl data (release 85)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2016-03-15.

• Database (version 84.01)
  • Update to Genomicus84.01 with the last Ensembl data (release 84)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2015-12-22.

• Database (version 83.01)
  • Update to Genomicus83.01 with the last Ensembl data (release 83)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2015-10-15.

• Database (version 82.01)
  • Update to Genomicus82.01 with the last Ensembl data (release 82)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2015-08-15.

• Database (version 81.01)
  • Update to Genomicus81.01 with the last Ensembl data (release 81)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2015-06-01.

• Database (version 80.01)
  • Update to Genomicus80.01 with the last Ensembl data (release 80)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2015-03-20.

• Database (version 79.01)
  • Update to Genomicus79.01 with the last Ensembl data (release 79)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2014-12-08.

• Database (version 78.01)
  • Update to Genomicus78.01 with the last Ensembl data (release 78)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Identical at 77.01

2014-11-05.

• Database (version 77.01)
  • Update to Genomicus77.01 with the last Ensembl data (release 77)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Search engine: queries can be done with gene description, gene name, CNE name, BlastP search
  • KaryoView and MatrixView are now available
  • New functionalities in PhyloView and AlignView (display of specific species), display according to gene size, display according to dN/dS ratio or Protein similarity

2014-08-24.

• Database (version 76.01)
  • Update to Genomicus76.01 with the last Ensembl data (release 76)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Search engine: queries can be done with gene description, gene name, CNE name, BlastP search
  • KaryoView and MatrixView are now available
  • New functionalities in PhyloView and AlignView (display of specific species), display according to gene size, display according to dN/dS ratio or Protein similarity

2014-04-20.

• Database (version 75.02)
  • Update to Genomicus75.01 with the last Ensembl data (release 75)
  • No Additionnal species
  • Genome-wide conserved non-coding elements (CNEs) are stored and represented with reference to the human genome. Their evolutionary linkage to their presumed target gene are indicated and displayed by "mouse-over" (Naville et al. submitted).
• Webcode
  • Search engine: queries can be done with gene description
  • KaryoView and MatrixView are now available
  • New functionalities in PhyloView and AlignView (display of specific species), display according to gene size

2014-03-15.

• Database (version 75.01)
  • Update to Genomicus75.01 with the last Ensembl data (release 75)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish
• Webcode
  • Search engine: queries can be done with gene description
  • KaryoView and MatrixView are now available
  • In PhyloView and AlignView: CNE can be sorted by specific phylla
  • New functionalities in PhyloView and AlignView (display of specific species)

2013-12-15.

• Database (version 74.01)
  • Update to Genomicus74.01 with the last Ensembl data (release 74)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish
• Webcode
  • Search engine: queries can be done with gene description
  • KaryoView and MatrixView are now available
  • In PhyloView and AlignView: CNE can be sorted by specific phylla
  • New functionalities in PhyloView and AlignView (display of specific species)

2013-10-15.

• Database (version 73.01)
  • Update to Genomicus73.01 with the last Ensembl data (release 73)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish
• Webcode
  • Search engine: queries can be done with gene description
  • KaryoView and MatrixView are now available
  • In PhyloView and AlignView: CNE can be sorted by specific phylla
  • New functionalities in PhyloView and AlignView (display of specific species)

2013-06-25.

• Database (version 72.01)
  • Update to Genomicus72.01 with the last Ensembl data (release 72)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish

2013-04-20.

• Database (version 71.01)
  • Update to Genomicus71.01 with the last Ensembl data (release 71)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish

2013-01-30.

• Database (version 70.01)
  • Update to Genomicus70.01 with the last Ensembl data (release 70)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish

2012-11-15.

• Database (version 69.01)
  • Update to Genomicus69.01 with the last Ensembl data (release 69)
  • No Additionnal species
  • All CNE positions for 10 species (Human, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish

2012-09-15.

• Database (version 68.02)
  • Update to Genomicus68.02 with the last Ensembl data (release 68)
  • No Additionnal species
  • All CNE positions for 10 species (Human version, Mouse, Dog, Cow, Chicken ,Opossum, Zebrafish, Tetraodon, Stickleback, Medaka) are available.
  • The current CNE set was generated with four levels of conservation:
    • Boreoeutheria: human + mouse + dog + cow
    • Mammals: human + mouse + dog + cow + Opossum
    • Amniotes: human + mouse + dog + cow + chicken
    • Vertebrates: human + mouse + dog + cow + chicken + fish

2012-08-15.

• Database (version 68.01)
  • Update to Genomicus68.01 with the last Ensembl data (release 68)
  • No Additionnal species
  • No CNE data

2012-05-20.

• Database (version 67.01)
  • Update to Genomicus67.01 with the last Ensembl data (release 67)
  • No Additionnal species
  • No CNE data

2012-03-05.

• Database (version 66.01)
  • Update to Genomicus66.01 with the last Ensembl data (release 66)
  • No Additionnal species
  • No CNE data

2012-02-15.

• Database (version 65.01)
  • Update to Genomicus65.01 with the last Ensembl data (release 65)
  • No Additionnal species
  • No CNE data

2011-09-21.

• Database (version 64.01)
  • Update to Genomicus64.01 with the last Ensembl data (release 64)
  • No Additionnal species
  • No CNE data (needs computation - intention for release Genomicus64.02)

2011-07-14.

• Database (version 63.01)
  • Update to Genomicus63.01 with the last Ensembl data (release 63)
  • No Additionnal species
  • All CNE positions for 5 species (Human version hg19, mus musculus mm9, Canis familiaris canFam2, Bos taurus v4, zebrafish zv9) are available.
  • The current CNE set was generated with three levels of conservation:
    • Set 1: human + mouse + dog + cow
    • Set 2: human + mouse + dog + cow + chicken
    • Set 3: human + mouse + dog + cow + chicken + zebrafish

2011-05-15.

• Database (version 62.02)
  • Update to Genomicus62.02 with the last Ensembl data (release 62)
  • Additionnal species:Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI
  • All CNE positions for 5 species (Human version hg19, mus musculus mm9, Canis familiaris canFam2, Bos taurus v4, zebrafish zv9) are available.
  • The current CNE set was generated with three levels of conservation:
    • Set 1: human + mouse + dog + cow
    • Set 2: human + mouse + dog + cow + chicken
    • Set 3: human + mouse + dog + cow + chicken + zebrafish

2011-04-15.

• Database (version 62.01)
  • Update to Genomicus62.01 with the last Ensembl data (release 62)
  • No Additionnal species
  • No CNE data (needs computation - intention for release Genomicus62.02)

2011-02-14.

• Database (version 61.01)
  • Update to Genomicus61.01 with the last Ensembl data (release 61)
  • No Additionnal species
  • No CNE data

2010-11-20.

• Database (version 60.01)
  • Update to Genomicus60.01 with the last Ensembl data (release 60)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI
  • New method of reconstruction of ancestral gene order (chromosome scale reconstruction is mostly achieved for mammals)
  • Optimized database table structure to speed-up rendering
• Webcode
  • Collapsed nodes are now symbolized by a filled triangle
  • Tree edition menu has been reworked (both views)
  • On the first page, the user can choose "Default view" to go to a compact PhyloView, or "Custom view" to select AlignView or Phyloview, and the depth of analysis
  • Various interface update
  • Various bugfixes
  • The website is fully compatible with HTML/XHTML/SVG/CSS standards, and thus with Firefox, Google Chrome and Safari

2010-09-15.

• Database (version 59.01)
  • Update to Genomicus59.01 with the last Ensembl data (release 59)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI

2010-06-28.

• Database (version 58.01)
  • Update to Genomicus58.01 with the last Ensembl data (release 58)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI

2010-03-15.

• Database (version 57.01)
  • Update to Genomicus57.01 with the last Ensembl data (release 57)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI

2010-01-22.

• Database (version 56.02)
  • Complete genome annotation of Branchiostoma floridae, Oikopleura dioica and Nematostella vectensis. Before this, only the genes with at least one homolog in any other species were displayed
• Webcode
  • Nodes in the tree can now be hidden to make the display clearer
  • In Phyloview, CNEs can be disabled
  • Data from the current view can be exported in a text file
  • The current display can be exported in a graphics file (SVG format). Users may then edit the figure and export it in PDF with softwares such as Inkscape
  • A statistics page gives information on the data used and reconstructed in Genomicus

2009-11-20.

• Database (version 56.01)
  • All CNE positions for new assembly (Human version hg19, Bos taurus v4, zebrafish zv8) are available.
  • The current CNE set was generated with three levels of conservation:
    • Set 1: human + mouse + dog + cow
    • Set 2: human + mouse + dog + cow + chicken
    • Set 3: human + mouse + dog + cow + chicken + zebrafish

2009-10-20.

• Database (version 56.01)
  • CNEs are temporarely removed. All CNE positions for new assembly (Human version hg19, Bos taurus v4, zebrafish zv8) will be available very soon.

2009-10-07.

• Database (version 56.01)
  • Update to Genomicus56.01 with the last Ensembl data (release 56)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI
  • Ancestors' genes names are infered from Ensembl protein trees' names (ENSGT000xxxx). FAMxxxx are still used when genes of the above additonal species are involved.
• Webcode
  • Support of Internet Explorer via Google Chrome Frame

2009-07-21.

• Database (version 55.01)
  • Update to Genomicus55.01 with the last Ensembl data (release 55)
  • Additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Sea anemone) from JGI, Branchiostoma floridae (Amphioxus) from JGI
• Webcode
  • Successive versions of Genomicus are now archived and available online. The new URL scheme is www.dyogen.ens.fr/genomicus for the most recent database and www.dyogen.ens.fr/genomicus-XX.XX for specific versions (permanent links)

2009-06-14.

• Database (version 54.01)
  • Update to Genomicus54.01 with the last Ensembl data (release 54)
  • additionnal species: Oikopleura dioica (Oikopleura) from Genoscope, Nematostella vectensis (Nematostella) from JGI, Branchiostoma floridae (Amphioxus) from JGI

2009-04-03.

• Webcode
  • In «AlignView», some situations with non-conserved gene neighbouring were represented with thicks lines instead of white space
  • Various optimisations that should improve server response

2009-03-20.

• Webcode
  • In «AlignView», gaps (thin/thicks lines) can now be queried and viewed in other browsers
  • In «Phyloview», modern species can now be hidden and low-coverage genomes can be automatically collapsed
  • Left & right arrows should be eaasier to click
  • In both views, zoom can be as wide as 45 genes displayed
  • Links to extern genome browser show the upstream and the downstream regions

2009-03-17.

• Webcode
  • The colour/symbol code is now consistent with Ensembl & TreeFam
  • The link to Ensembl GeneView is now working
  • Our mail adress has changed and now works

2009-03-12.

• Webcode
  • A «alignment view» is now available, and the previous mode of display is now «Phyloview». A button allows to switch between both views without starting a new search
  • A two-state button 'Reference order'/'Adaptative order' changes the order of modern species to highlight the genome evolution from the root species to the current reference species
• Database (version 53.01)
  • Synteny blocks have been updated with the last Ensembl data (release 53). Thanks to the addition of new key amniote genomes such as zebra finch or lizard, synteny blocks are much longer at Amniota & Mammalia nodes

2008-11-01.

• Webcode
  • The menu to select extant and ancestral species has been tidyed up
  • A history page has been added
  • Some links to customize the tree view have been added
  • The search engine now displays a message when the query gene has no orthologues
• Database (version 50.02)
  • A bug in the display of amphioxus genes has been corrected: most genes were previously shown below an artefactual duplication node, which have now been removed. This does not affect the number of amphioxus genes displayed nor their phylogenic relationship with other species
  • Now only duplication nodes with a confidence index (as provided by Ensembl) of 0.3 or more are taken into account. Duplication nodes below this value are propagated to terminal branches and thus turned into species specific duplications. The consequence is the removal of several thousand ancestral genes per ancestral species which were likely artefactual. Syntenic blocks are now longer and more reliable

2008-10-01.

• Initial release of the browser
• Database version 50.01

Version scheme.

• The web-code is referred with the date of its release
• The database version is composed of two numbers:
  • The version of the Ensembl database used to define the gene annotations and the protein trees
  • The version of the reconstructions (synteny, ancestral gene order & conserved non-coding elements)